ATCC 51299 粪肠球菌耐万古霉素 百欧博伟生物
小杨 / 2022-10-27 09:10:43
耐万古霉素肠球菌指肠球菌在使用糖肽类抗菌药物（万古霉素）治疗过程中，其自身代谢和结构发生改变，使细菌对糖肽类（万古霉素）抗菌药物敏感性下降，甚至出现敏感性完全丧失。
菌种简介
平台编号：Bio-72812
规格：Freeze-Dried
拉丁属名：Enterococcus Faecalis
菌株名称：粪肠球菌耐万古霉素
用途：ATCC原装进口
注意事项：仅用于科学研究或者工业应用等非医疗目的不可用于人类或动物的临床诊断或治疗，非药用，非食用（产品信息以出库为准）
详细描述
Enterococcus faecalis (Andrewes and Horder) Schleifer and Kilpper-Balz 拉丁名
(ATCC? 51299?) 统一编号
Strain Designations 菌种别名: NJ-3
Type Strain 模式菌种 : no
Biosafety Level 生物安全等级 : 2
Strain Designations 菌种别名 NJ-3
Application 用途 Quality control strain Susceptibility disc testing
Susceptibility testing Isolation Peritoneal fluid, St. Louis, MO
Biosafety Level 生物安全等级 2
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Product Format 提供形式 freeze-dried
Storage Conditions 保藏方法
Frozen（冷冻物）: -80℃ or colder
Freeze-Dried（冻干物）: 2℃ to 8℃
Live Culture（活物）: See Propagation Section
Preceptrol? yes Genotype vanB ant(6)-I aac(6') aph(2"")
Type Strain 模式菌株 no
Antibiotic Resistance Low-level vancomycin-resistant, VanB Resistant to Vancomycin. Sensitive to Teichoplanin. Comments Presence of vanB confirmed by PCR Ref
Medium 培养基 ATCC? Medium 2174: Brain heart infusion medium with vancomycin 4 mcg/ml
Growth Conditions 生长条件
Temperature 培养温度 : 37℃
Atmosphere 需氧情况: Aerobic
Genotype vanB ant(6)-I aac(6') aph(2"")
Name of Depositor 寄存人 FC Tenover Chain of Custody ATCC <-- FC Tenover <-- J Hoppe-Bauer
Isolation 分离源 Peritoneal fluid, St. Louis, MO
References 参考文献 Tenover FC, et al. Ability of clinical laboratories to detect antimicrobial agent- resistant enterococci [published erratum appears in J. Clin. Microbiol. 31: 3081, 1993]. J. Clin. Microbiol. 31: 1695-1699, 1993. PubMed: 8349745
Swenson JM, et al. Molecular characterization and multilaboratory evaluation of Enterococcus faecalis ATCC 51299 for quality control of screening tests for vancomycin and high-level aminoglycoside resistance in enterococci. J. Clin. Microbiol. 33: 3019-3021, 1995. PubMed: 8576364
Performance Standards for Antimicrobial Disk Susceptibility Tests; Approved Standard - 9th Edition. Wayne, PA. Clinical and Laboratory Standards Institute; CLSI M2-A9. Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow Aerobically; Approved Standard - 7th Edition. Wayne, PA. Clinical and Laboratory Standards Institute; CLSI M7-A8.
Performance Standards for Antimicrobial Disk and Dilution Susceptibility Tests for Bacteria Isolated from Animals; Approved Standard - 2nd Edition. Wayne, PA. Clinical and Laboratory Standards Institute; CLSI M31-A3. Performance Standards for Antimicrobial Susceptibility Testing; Sixteenth Informational Supplement. Wayne, PA. Clinical and Laboratory Standards Institute; CLSI M100-S20, 2007
BD Phoenix Gram Positive AST PMIC/ID QC Set. BD Becton Dickinson; Phoenix MicroScan Dried Gram Positive Panel QC Set. Dade/Siemens.
Sensititre? MIC Susceptibility. Thermo Scientific? Sensititre? Systems, Trek Diagnostic Systems.
VITEK 2 AST-GP QC Set. bioMerieux.
MicroScan Synergies plus Gram Positive QC Set. Dade/Siemens.
BD GeneOhm VanR QC Set. BD Becton Dickinson.
ISO/CD 11133:2009, Annex E. Test microorganisms for commonly used culture media (giving information on the culture medium, culture conditions, test microorganisms, culture collection number of test organisms and the expected reactions)
Corry, JEL, Curtis, GDW and Baird, RM (Eds) Handbook of Culture Media for Food and Water Microbiology. Royal Society of Chemistry, In preparation. ICFMH-WPCM.
Patel R, et al. Multiplex PCR Detection of vanA, vanB, vanC-1, and vanC-2/3 Genes in Enterococci. J. Clin. Microbiol. 35(3): 703-707, 1997. PubMed: 9041416
药理信息
肠球菌属通常存在于人体肠道和女性生殖道中，而且常常存在于环境中，这类细菌可造成感染。万古霉素常常作为治疗肠球菌属感染的最后有效抗菌药物，某些情况下，肠球菌属对万古霉素产生耐药（若MIC=16ug/ml，则肠球菌对万古霉素中敏；若16ug/ml∠MIC∠64ug/ml,则需应用E试验来确定肠球菌对万古霉素耐药；若MIC≥64ug/ml则确认为肠球菌对万古霉素耐药），这类细菌称为耐万古霉素肠球菌（VRE），大多数的VRE感染通常发生在医院内。
微生物菌种查询网作为中国微生物菌种中心引航者，单位代为引进美国ATCC微生物菌种保藏中心，德国DSMZ菌种保藏中心，荷兰CBS菌种保藏中心，日本JCM微生物菌种保藏中心，包括其中的ATCC微生物细菌与噬菌体（18382）；细胞系和杂交瘤（4997）；真菌和酵母（58183）；原代细胞（146）；原生动物和藻类（2428）；干细胞（102）；载体，克隆与分子（18006）；病毒（3594）；核酸 - DNA / RNA（1350），引进进口微生物菌种货期短，质量保证，UPS国际快递运输。