鼠李糖乳杆菌（LGG）是一种无毒、无副作用的益生菌，其功能特性主要有调节肠道菌群、预防和治疗腹泻、毒素的排出和提升机体免疫力，具有较高的应用价值，符合现代人类健康保健的基本需求。鉴于鼠李糖乳杆菌的功能特性，使得LGG可以添加到发酵乳制品中，结合食品科学，具有极高的应用价值和发展前景。
菌种简介
平台编号：Bio-67385
规格：Freeze-Dried
拉丁属名：Lactobacillus Rhamnosus
菌株名称：鼠李糖乳杆菌
用途：ATCC原装进口
注意事项：仅用于科学研究或者工业应用等非医疗目的不可用于人类或动物的临床诊断或治疗，非药用，非食用（产品信息以出库为准）
详细信息
Lactobacillus rhamnosus 菌株拉丁名 (Hansen) Collins et al.
(ATCC? 7469?) 菌株编号
Strain Designations菌株别名 : [BUCSAV 227, M. Rogosa V300, M.E. Sharpe H2, NCDO 243, NCIB 6375, NCIB 8010, NCTC 6375, NRC 488, P.A. Hansen 300, R.P. Tittsler 300]
Type Strain模式菌株: yes
Biosafety Level 生物安全等级 : 1
Deposited As Lactobacillus casei (Orla-Jensen) Holland
Application 菌株用途 Assay of folic acid
Assay of niacinamide nicotinamide
Assay of riboflavin vitamin B2
Produces folate transport protein
Food testing
Type Strain 模式菌株 yes Ref, (. Type strains of Lactobacillus species. Rockville, MD: ATCC; 1960.), Ref
Product Format 提供形式 freeze-dried
Storage Conditions 保藏方法
Frozen（冷冻物）: -80℃ or colder
Freeze-Dried（冻干物）: 2℃ to 8℃
Live Culture（活菌）: See Propagation Section
Preceptrol? yes
Type Strain 模式菌株 yes Ref, (. Type strains of Lactobacillus species. Rockville, MD: ATCC; 1960.), Ref
Comments Respiratory physiology
Extraction of acidic metabolites
Pyruvate utilization
Medium 培养基 ATCC? Medium 416: Lactobacilli MRS Agar/Broth
Growth Conditions 生长条件
Temperature 培养温度 : 37℃
Atmosphere 需氧情况: 5% CO2
Name of Depositor 寄存人FM Strong
References 参考文献 Henderson GB, et al. Kinetic evidence for two interconvertible forms of the folate transport protein from Lactobacillus casei. J. Bacteriol. 163: 1147-1152, 1985. PubMed: 3928596
Colwell RR, Liston J. Taxonomic relationships among the pseudomonads. J. Bacteriol. 82: 1-14, 1961. PubMed: 13694873
Biochem. J. 69: 403, 1958.
Biochim. Biophys. Acta 54: 614, 1961.
Biochim. Biophys. Acta 59: 273, 1962.
Biochim. Biophys. Acta 71: 454, 1963.
Ikawa M. Nature of the lipids of some lactic acid bacteria. J. Bacteriol. 85: 772-781, 1963. PubMed: 14044942
Sharpe ME. A serological classification of lactobacilli. J. Gen. Microbiol. 12: 107-122, 1955. PubMed: 14354139
Davis GH. The classification of Lactobacilli from the human mouth. J. Gen. Microbiol. 13: 481-493, 1955. PubMed: 13278499
Sharpe ME, Wheater DM. Lactobacillus helveticus. J. Gen. Microbiol. 16: 676-679, 1957. PubMed: 13439152
Clin. Chem. 5: 275, 1959.
J. Appl. Bacteriol. 18: 274, 1955.
J. Biol. Chem. 157: 303, 1945.
Arch. Biochem. 16: 357-360, 1948.
Nature 149: 696, 1942.
J. Clin. Pathol. 14: 335, 1961.
Zentralbl. Bakteriol., II Abt. 111: 250, 1958.
Abo-Elnaga IG, Kandler O. Zur taxonomier der Gattung Lactobacillus Beijerinck. I. Das subgenus Streptobacterium Orla-Jensen. Zentralbl. Bakteriol., II Abt. 119: 1-36, 1965.
Rogosa M, et al. Species differentiation of oral lactobacilli from man including description of Lactobacillus salivarius nov. spec. and Lactobacillus cellobiosus nov. spec.. J. Bacteriol. 65: 681-699, 1953. PubMed: 13069442
Birnbaum J, Lichstein HC. Metabolism of biotin and analogues of biotin by microorganisms. IV. Degradation of biotin, oxybiotin, and desthiobiotin by Lactobacillus casei. J. Bacteriol. 92: 925-930, 1966. PubMed: 5926760
J. Gen. Microbiol. 37: 433-438, 1964.
Brown JP, VanDemark PJ. Respiration of Lactobacillus casei. Can. J. Microbiol. 14: 829-835, 1968. PubMed: 4385940
Benito de Cardenas IL, et al. Utilization of pyruvate in Lactobacillus casei subsp. rhamnosus ATCC 7469. Curr. Microbiol. 15: 259-264, 1987.
Collins MD, et al. Deoxyribonucleic acid homology studies of Lactobacillus casei, Lactobacillus paracasei sp. nov., subsp. paracasei and subsp. tolerans, and lactobacillus rhamnosus sp. nov., comb. nov.. Int. J. Syst. Bacteriol. 39: 105-108, 1989.
Doelle HW, Manderson GJ. Preparation of extracts of culture liquids for gas-chromatographic determination of acidic fermentation products. Antonie van Leeuwenhoek 35: 467-478, 1969. PubMed: 5311575
Type strains of Lactobacillus species. Rockville, MD: ATCC; 1960.
AOAC International Vitamin assays, microbiological method. Gaithersburg, MD:AOAC International;AOAC "Official Methods of Analysis of the AOAC International" 960.46.
AOAC International Folic acid (pteroylglutamic acid) in infant formula, microbiological methods. Gaithersburg, MD:AOAC International;AOAC "Official Methods of Analysis of the AOAC International" 992.05.
Crowley PJ, et al. Genetic and physiologic analysis of a formyl-tetrahydrofolate synthetase mutant of Streptococcus mutans. J. Bacteriol. 179: 1563-1572, 1997. PubMed: 9045814
Debabov DV, et al. The D-Alanyl carrier protein in Lactobacillus casei: cloning, sequencing, and expression of dltC. J. Bacteriol. 178: 3869-3876, 1996. PubMed: 8682792
Skerman VB, et al. Approved lists of bacterial names. Int J Syst Bacteriol 30: 225-420, 1980.
Girdwood RH. The microbiological assay of vitamins and amino acids. J. Med. Lab. Technol. 20: 26-33, 1963. PubMed: 13948188
type strain
Total Folates in Cereals and Cereal Foods. Gaithersburg, MD:AOAC International;AOAC "Official Methods of Analysis of the AOAC International" 2004.05.
Total folate in cereal products-microbiological assay using trienzyme extraction.. St. Paul, MN, 2000
Foodstuffs --- Determination of folate by microbiological assay. London, UK:British Standards Institution;British Standard BS EN 14131:2003.
ISO/CD 11133:2009, Annex E. Test microorganisms for commonly used culture media (giving information on the culture medium, culture conditions, test microorganisms, culture collection number of test organisms and the expected reactions)
Corry, JEL, Curtis, GDW and Baird, RM (Eds) Handbook of Culture Media for Food and Water Microbiology. Royal Society of Chemistry, In preparation. ICFMH-WPCM.
Collins MD, et al. Deoxyribonucleic acid homology studies of Lactobacillus casei, Lactobacillus paracasei sp. nov., subsp. paracasei and subsp. tolerans, and lactobacillus rhamnosus sp. nov., comb. nov.. Int. J. Syst. Bacteriol. 39: 105-108, 1989.
Type strains of Lactobacillus species. Rockville, MD: ATCC; 1960.
Skerman VB, et al. Approved lists of bacterial names. Int J Syst Bacteriol 30: 225-420, 1980.
Collins MD, et al. Deoxyribonucleic acid homology studies of Lactobacillus casei, Lactobacillus paracasei sp. nov., subsp. paracasei and subsp. tolerans, and lactobacillus rhamnosus sp. nov., comb. nov.. Int. J. Syst. Bacteriol. 39: 105-108, 1989.
Type strains of Lactobacillus species. Rockville, MD: ATCC; 1960.
Skerman VB, et al. Approved lists of bacterial names. Int J Syst Bacteriol 30: 225-420, 1980.
Cross References
Nucleotide (GenBank) : AF192553 Lactobacillus rhamnosus dlt operon, complete sequence.
Nucleotide (GenBank) : L08854 Lactobacillus casei valyl-tRNA synthetase gene, complete cds.
Nucleotide (GenBank) : J05221 L.carei folylpoly-gamma-glutamate synthetase gene, complete cds.
Nucleotide (GenBank) : AF323539 Lactobacillus rhamnosus strain ATCC 7469 glycosyltransferase gene, partial cds.
Nucleotide (GenBank) : AF323528 Lactobacillus rhamnosus strain ATCC 7469 priming glycosyltransferase gene, partial cds.
Nucleotide (GenBank) : U43894 Lactobacillus casei dlt operon DltA, DltB, and DltC genes, complete cds, and DltD gene, partial cds.
Nucleotide (GenBank) : M83993 Lactobacillus casei D-alanine-activating enzyme gene, complete cds and a potential basic membrane protein (involved in D-ala-LTA biosynthesis) gene, 5' end.
Nucleotide (GenBank) : AF015453 Lactobacillus rhamnosus 6-phospho-beta-glucosidase homolog gene, partial cds; GNTR transcriptional regulator homolog and surface located protein genes, complete cds.
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