ATCC® Number:VR-260™ 统一编号
Classification: Herpesviridae, Simplexvirus
Agent: Human herpesvirus 1 deposited as Herpes simplex virus 1
Strain: HF
Original Source: Vesicle fluid from patient with recurrent herpes simplex, New York, 1922
Depositors: KL Herrmann
Biosafety Level 生物安全等级 :2
Shipped 提供形式 : frozen
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Host Organism : Vero cells (ATCCCCL-81), CE(CAM) chicken embryo (chorioallantoic membrane and yolk sac) rabbit cornea; mouse, i.c. inoculation; rabbit kidney in tissue culture cells; human fibroblast cells
Incubation :
Duration:2-3 days at 37.0°C
Effect : Yes, in vitro effects: Cytopathic effects (syncytia, rounding, detachment) in tissue culture; lesions on chorioallantoic membrane
Comments 注释 : This strain is recommended by ATCCfor use in the tests described in Fed. Spec. A-A-1438 where only the taxon is specified.
This Herpes simplex virus strain was originally adapted for growth in CE tissues.
Pocks on CAM tend to be larger than those produced by other HSV-1 strains.
Large inocula are required to infect animals.
Confirmed as type 1 by FA in 1991 at ATCC.
References : 33435: Flexner S. . J. Exp. Med. 41: 215, 1925. 33436: Flexner S. . J. Exp. Med. 47: 9, 1928.