ATCC® Number:50583™
Organism: Giardia intestinalis (Lambl) Alexeieff
Designations: WB clone A6
Depositors: TE Nash
Biosafety Level:2
Shipped: frozen
Growth Conditions: ATCCmedium 2155: LYI Giardia Medium (filtered)Temperature: 35.0°C Duration: axenic; anaerobic
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Comments: Antigenic variation in vivo [21665] Antigenic variation [21666] Association of variant surface antigens with thick cell coat [21668] Induction of differentiation by cholesterol starvation [21669] Variant specific epitopes [21709]
Classification: KINGDOM: Archeozoa
References: 21665: Aggarwal A, Nash TE. Antigenic variation of Giardia lamblia in vivo. Infect. Immun. 56: 1420-1423, 1988. PubMed: 3372015 21666: Nash TE, et al. Antigenic variation in Giardia lamblia. J. Immunol. 141: 636-641, 1988. PubMed: 2454999 21668: Pimenta PF, et al. Variant surface antigens of Giardia lamblia are associated with the presence of a thick cell coat: Thin section and label fracture immunocytochemistry survey. Infect. Immun. 59: 3989-3996, 1991. PubMed: 1937758 21669: Lujan HD, et al. Cholesterol starvation induces differentiation of the intestinal parasite Giardia lamblia. Proc. Natl. Acad. Sci. USA 93: 7628-7633, 1996. PubMed: 8755526 21709: Nash TE, et al. Variant specific epitopes of Giardia lamblia. Mol. Biochem. Parasitol. 42: 125-132, 1990. PubMed: 1700296