ATCC® Number:VR-1098™
Classification: Adenoviridae, Mastadenovirus, Human adenovirus B
Agent: Human adenovirus 21 deposited as Adenovirus type 21
Strain: AV-1645 [V-221-011-014]
Original Source: Presumed from conjunctival scrapings from child with trachoma, Saudi Arabia, 1956
Depositors: NIH/NIAID
Biosafety Level:2
Shipped: frozen
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Host Organism : Chang C cells (ATCCCCL-20.2) Chang C cells (ATCCCCL-20.2); KB cells (ATCCCCL-17); human embryonic kidney cells
Effect : Yes, in vitro effects: Cytopathic effects in tissue culture
Comments : Replicates slowly. Weakly oncogenic. Agglutinates rhesus but not rat RBC. REFERENCE STRAIN: Pereira, H.G. et al., Virology 20: 613, 1963.
References : 24520: Bell SD. . Am. J. Trop. Med. Hyg. 9: 523, 1960. 24704: Hierholzer JC, et al. Antigenic relationships among the 47 human adenoviruses determined in reference horse antisera. Arch. Virol. 121: 179-197, 1991. PubMed: 1759904 32356: Ma Y, Mathews MB. Structure, function, and evolution of adenovirus-associated RNA: a phylogenetic approach. J. Virol. 70: 5083-5099, 1996. PubMed: 8764016