ATCC® Number:VR-452™
Classification: Reoviridae, Rotavirus
Agent: Calf rotavirus
Strain: Lincoln
Original Source: Intestinal contents of diarrheic calf
Depositors: EP Bass
Biosafety Level:2
Shipped: frozen
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Host Organism : fetal bovine kidney cells fetal bovine kidney cells; African green monkey kidney cells
Incubation : Temperature: 35.0°C Duration: 3-5 days
Effect : Yes, in vitro effects: Cytopathic effects (granulated appearance of cells, rounding and detachment from surface)
Comments : VR-452 is antigenically distinct from bovine rotavirus VR-1290 by neutralization. Attenuated strain.
References : 33597: Mebus CA, et al. Cell culture propagation of neonatal calf diarrhea (scours) virus. Can. Vet. J. 12: 69-72, 1971. PubMed: 4933992 33598: Fernelius AL, et al. Cell culture adaptation and propagation of a reovirus-like agent of calf diarrhea from a field outbreak in Nebraska. Arch. Gesamte Virusforsch. 37: 114-130, 1972. PubMed: 4623479 33599: Welch AB, Thompson TL. Physiochemical characterization of a neonatal calf diarrhea virus. Can. J. Comp. Med. 37: 295-301, 1973. PubMed: 4270437