ATCC® Number:VR-802™
Classification: Picornavirus, Cardiovirus, Animal
Agent: Rat encephalomyelitis
Strain: MHG
Original Source: Adult laboratory rats
Depositors: IE Hemelt, DL Huxsoll, EH Stephenson
Biosafety Level:2
Shipped: frozen
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Host Organism : suckling rat; suckling mouse
Incubation : Duration: 5 days in suckling rat; 6 days in sM
Effect : Yes, in vivo effects: Paralysis of one or more limbs, disorientation, ruffled fur, arching of back and emaciation
Comments : Measures approximately 17 to 27 nm in diameter. Resistant to ether, chloroform and sodium deoxycholate. Stable at pH 3.0. Does not hemagglutinate human O cells or sheep, goose, rat, rooster, guinea pig erythrocytes. Measures approximately 17 to 27 nm in diameter. Resistant to ether, chloroform and sodium deoxycholate. Stable at pH 3.0. Does not hemagglutinate human O cells or sheep, goose, rat, rooster, guinea pig erythrocytes.
References : 33902: McConnell SJ, et al. Isolation and characterization of a neurotropic agent (MHG virus) from adult rats. Proc. Soc. Exp. Biol. Med. 115: 362-367, 1964. PubMed: 14121611