ATCC® Number:VR-134™
Classification: Arenaviridae, Arenavirus
Agent: Lymphocytic choriomeningitis virus
Strain: Armstrong E-350
Original Source: clinical specimen - human Isolation date: 1933 Isolated from monkeys initially inoculated with material from a human patient, St. Louis encephalitis epidemic of 1933
Depositors: EH Lennette, R Emmons
Biosafety Level:3
Shipped: freeze-dried
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Host Organism : Cavia porcellusSaguinus oedipusMus musculusSaguinus tripartitusMacaca mulattaCebus sp.mouse, i.c. inoculation monkey; mouse; guinea pig
Incubation : Duration: 5-6 days
Effect : Yes, in vivo effects: dealth in suckling mice (i. c. inoculation)
Comments : Low virulence for GP when injected by s.c. route. This is the first strain of this virus isolated and identified; it has been used since 1933 in the Public Health Service as the standard strain of this agent. LCM is highly infectious and may infect laboratory workers or invade animal colonies. See Hellman et al. (1975: Amer. J. Epidem. 101:103) for information on human infections. Armstrong E-350 strain can be used for immunizing guinea pigs. Low virulence for GP when injected by s.c. route. This is the first strain of this virus isolated and identified; it has been used since 1933 in the Public Health Service as the standard strain of this agent.
Related Products: also distributed as:ATCC VR-1271