ATCC® Number:VR-24™
Agent: Measles virus
Strain: Edmonston
Original Source: Blood from patient in acute phase of typical measles, Massachusetts, 1954
Depositors: JF Enders
Biosafety Level:2
Shipped: frozen
Permits/Forms: In addition to the MTA mentioned above, other ATCC and/or regulatory permits may be required for the transfer of this ATCC material. Anyone purchasing ATCC material is ultimately responsible for obtaining the permits. Please click here for information regarding the specific requirements for shipment to your location.
Incubation : Atmosphere: humidity in air, 95%; carbon dioxide (CO2), 5% Temperature: 37.0°C Duration: 4-14 days
Effect : Yes, in vitro effects: Cytopathic effects (syncytial rounding and sloughing )
Comments : The virus can be adapted to grow in chick embryo cell culture. A CE adapted Edmonston strain has been used for the production of vaccines for human use. Measles, rinderpest and canine distemper viruses contain a common antigen.
References : 33416: Enders JF, Peebles TC. Propagation in tissue cultures of cytopathogenic agents from patients with measles. Proc. Soc. Exp. Biol. Med. 86: 277-286, 1954. PubMed: 13177653