ATCC® Number:VR-1412™
Classification: Retroviridae,Gammaretrovirus,Mammalian virus group
Agent: Murine leukemia virus
Strain: Rauscher (biologically cloned)
Original Source: Mouse spleen
Depositors: JW Hartley
Biosafety Level:2
Shipped: frozen
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Host Organism : NIH/3T3 cells (ATCCCRL-1658) mouse; mouse cells
Incubation : Temperature: 37.0°C Duration: 1 day in TC; 5-9 days for XC-assay
Effect : Yes, in vitro effects: Cytopathic effects (plaque formation) only in XC-assay and in mouse S+L- cells
Comments : Infects mouse embryo fibroblast cultures of Fv-1(b) or Fv-1(n) strains and SC-1 cells.
References : 33072: Rauscher FJ. A virus-induced disease of mice characterized by erythrocytopoiesis and lymphoid leukemia. J. Natl. Cancer Inst. 29: 515-543, 1962. PubMed: 14490596 33075: Hartley JW, et al. Complement fixation and tissue culture assays for mouse leukemia viruses. Proc. Natl. Acad. Sci. USA 53: 931-938, 1965. PubMed: 4287967