ATCC® Number:VR-2043™
Classification: Poxviridae, Orthopoxvirus
Agent: Vaccinia virus
Strain: vP-9 [recombinant Vaccinia virus]
Depositors: E Paoletti
Biosafety Level:2
Shipped: frozen
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Host Organism : HeLa cells (ATCCCCL-2); CV-1 (ATCCCCL-70); Vero (ATCCCCL-81)
Effect : Yes, in vitro effects: Cytopathic effects in tissue culture
Comments : vP-9 (ATCCVR-2043) and vP-10 (ATCCVR-2044) contain the same insert but in opposite orientations. [13130] Recombinant vaccinia containing influenza HA gene. HA antigen is expressed in vivo. Recombinant vaccinia containing influenza HA gene. HA antigen is expressed in vivo. Expresses the hemagglutinin gene (serotype H1) and can be used in the production of antibodies against this protein. [13130]
References : 13123: Paoletti E, Panicali D. Modified vaccinia virus. US Patent 4,603,112 dated Jul 29 1986 13130: Paoletti E, Panicali D. Method for immunizing animals with synthetically modified vaccinia virus. US Patent 4,722,848 dated Feb 2 1988 13139: Panicali D, et al. Two major DNA variants present in serially propagated stocks of the WR strain of vaccinia virus. J. Virol. 37: 1000-1010, 1981. PubMed: 6262520